WebCyclooxygenase-2 COX-2 P35354 CHEMBL230 2,855 Dihydrofolate reductase Dihydrofolate P00374 CHEMBL202 584 Dopamine D2 receptor Dopamine P14416 CHEMBL217 479 Norepinephrine transporter Ephrin P23975 CHEMBL222 1,740 Epidermal growth factor receptor erbB1 erbB1 P00533 CHEMBL203 4,868 ... WebMay 5, 2015 · Cyclooxygenase-2 (CHEMBL - CHEMBL230) Inhibition of IL-1 beta-induced LOX activity in human SW982 cells assessed as enzyme activity at LD50 treated for 24 hrs prior to incubation with IL-1 beta for 6 hrs (Rvb = 100.0%) (CHEMBL - CHEMBL3428985)
ChEMBL 20 Released - GitHub Pages
WebAs a member of the wwPDB, the RCSB PDB curates and annotates PDB data according to agreed upon standards. The RCSB PDB also provides a variety of tools and resources. … WebCHEMBL230 Cyclooxygenase-2 myocardial infarction, increased blood pressure, ischaemic stroke, atherothrombosi28,67 CHEMBL340 Cytochrome P450 3A4 drug-drug interactions, detoxification by metabolism, activation of toxic metabolites68 CHEMBL240 HERG QT interval prolongation69 CHEMBL2039 Monoamine oxidase B cell death70 r kelly gets beat up in prison
The ChEMBL bioactivity database: an update
WebFeb 3, 2015 · Pesticide MoA classification For molecules in ChEMBL that are known pesticides, we have included the mode of action classification assigned by the Fungicide … WebDescription DOI: 10.1016/j.ejmech.2012.01.053 Target ChEMBL ID: CHEMBL230 ChEMBL Target Name: Cyclooxygenase-2 ChEMBL Target Type: SINGLE PROTEIN - Target is a single protein chain Relationship Type: D - Direct protein target assigned Confidence: Direct single protein target assigned PubChem 3 Result Definitions PubChem 4 Data Table … WebSeveral enzymes with available biological activity and 3D structure data were selected and investigated in this study. Chemical compounds were selected with known activity against the following enzymes: JNK-3 (CHEMBL2637), PTP1B (CHEMBL335), NFR2 (CHEMBL1075094), NOX1 (CHEMBL1287628), PDE5 (CHEMBL1827), COX-2 … r kelly getting out of jail 2022