Early growth response protein 1
EGR-1 (Early growth response protein 1) also known as ZNF268 (zinc finger protein 268) or NGFI-A (nerve growth factor-induced protein A) is a protein that in humans is encoded by the EGR1 gene. EGR-1 is a mammalian transcription factor. It was also named Krox-24, TIS8, and ZENK. It was originally discovered in mice. See more The protein encoded by this gene belongs to the EGR family of Cys2His2-type zinc finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for … See more The DNA-binding domain of EGR-1 consists of three zinc finger domains of the Cys2His2 type. The amino acid structure of the EGR-1 zinc finger domain is given in this table, using the … See more EGR-1 has been shown to interact with: • CEBPB, • CREB-binding protein, • EP300, • NAB1, See more • Zif+268+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • FactorBook Egr-1 • Overview of all the structural information available in the PDB for UniProt: P18146 (Human Early growth response protein 1) at the See more EGR-1 binds the DNA sequence 5'-GCG TGG GCG-3' (and similar ones like 5'-GCG GGG GCG-3'). The f1 position 6 binds the 5' G (the first base count from the left); the f1 … See more • Zinc finger See more • Heath RG (March 1975). "Brain function and behavior. I. Emotion and sensory phenomena in psychotic patients and in experimental … See more WebJan 7, 2010 · The gene encoding early growth response protein 1 (EGR-1) is a member of the immediate-early gene family and is rapidly induced by various mitogens, growth …
Early growth response protein 1
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WebMay 9, 2003 · Early growth response protein 3 Gene Egr3 Status UniProtKB reviewed (Swiss-Prot) Organism Mus musculus (Mouse) Amino acids 387 Protein existence Evidence at transcript level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Download Add a publication Entry feedback Function WebHowever, growth was detected (~1.2 doublings d −1) over this 18 h period (including in the N- treatment) indicating cultures had not yet become growth-limited or N-starved by the end of the experiment and cells were likely in early stages of sensing reductions in N availability .
WebEarly growth response protein 1 (Egr-1): prototype of a zinc-finger family of transcription factors Prog Nucleic Acid Res Mol Biol. 1995;50:191-224. doi: 10.1016/s0079 … WebEGR1. Early growth response protein 1 (Egr1) is a transcription factor that is rapidly induced by growth factors, cytokines, and stress signals such as radiation, injury, or …
WebMar 9, 2024 · Egr proteins play an important role in controlling insulin biosynthesis, glucose homeostasis, and islet size of pancreatic beta-cells in vivo PKCdelta mediates ERK and JNK activation in the LPA signaling pathway and that this pathway is required for LPA-induced gene regulation as evidenced by Egr-1 expression. WebMay 22, 2024 · Importance of Ca 2+ and Ca 2+ regulators. Ca 2+ is involved in cellular excitation and is an important second messenger. In a resting cell, typical intracellular Ca …
WebEarly growth response proteins are a family of zinc finger transcription factors. Members of the family include: EGR1, EGR2, EGR3 and EGR4; References
WebApr 4, 2024 · Next Generation Sequencing for Potential Regulated Genes and Micro-RNAs of Early Growth Response-1 in the Esophageal Squamous Cell Carcinoma. Tseng YC, … nottinghill family wellnessWebNov 10, 2024 · Early growth response‐1 (Egr‐1) is a master regulator and transcriptional sensor in vascular dysfunction and disease. This article … nottinghamshire villagesWebMar 24, 2024 · Early growth response factor 1 (EGR1) is a transcription factor that is mainly involved in the processes of tissue injury, immune responses, and fibrosis. … nottinghill collection 1light chandlierWebDose-response relationships were evident when subjects were categorized into quartiles by the values of IGF-1, IGF binding protein-3 and the molar ratio in controls. To our knowledge this is the first study to suggest that patients with bladder cancer have higher plasma levels of IGF-1 and lower levels of IGF binding protein-3 than controls. how to show ping and fps in rustWebEarly growth response protein 1 (Egr1) is a transcription factor that is rapidly induced by growth factors, cytokines, and stress signals such as radiation, injury, or mechanical … how to show ping dota 2WebProstate cancer is the most prevalent malignancy and the second leading cause of cancer mortality in men. Early growth response gene-1 (EGR-1) plays a crucial role in the … nottinghill churchWebMar 6, 2024 · The immediate early gene and transcription factor early growth response 1 (EGR1) has thus been revealed as a major mediator and regulator of synaptic plasticity … nottinghill family wellness centre