WebThe use of a dominant-negative mutant of IRF-8\ICSBP designed to serve as a molecular tool to dissociate the role of the various protein-protein interactions is described and the … Web17 apr. 2015 · The NF-κB and IRF transcription factor families are major players in inflammation and antiviral response and act as two major effectors of the innate immune …
Regulation of the type I IFN induction: a current view
Web29 nov. 2024 · IFN-I is the key regulatory component activating and modulating the response of innate and adaptive immune system to bacterial as well as viral pathogens. … Web21 mrt. 2024 · IRF1 (Interferon Regulatory Factor 1) is a Protein Coding gene. Diseases associated with IRF1 include Lung Cancer and Gastric Cancer . Among its related … rav god of war
UniProt
WebWe report the definition of a functional regulatory element in the VCAM1 promoter interacting with the transcriptional activator interferon regulatory factor 1 (IRF-1). DNA … Web29 sep. 2024 · For example, interferon regulatory factor-1 (IRF-1), the member of the IRF family, is highly expressed in IFN-γ stimulated cells. Its activation induces the expression of a variety of genes involved in biological processes such as cell cycle regulation, apoptosis, growth inhibition, and tumor suppression [ 34 ]. Web22 mrt. 2010 · We examined the molecular alterations induced by the transcriptional activator IFN regulatory factor (IRF)-1 and found viperin to be among the group of IRF … ravfour numbernumber hybrid