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WebKamailio - The Open Source SIP Server for large VoIP and real-time communication platforms - - kamailio/ims_isc_mod.c at master · kamailio/kamailio WebMar 15, 2024 · Within this category, patients with a high TMB had a 15.3% overall response rate, which was actually lower than the response rate for patients with low TMB. “While TMB status does show value in predicting response to immune checkpoint blockade in several cancer types, this was not generalizable across all cancers,” McGrail said. WebDec 27, 2024 · This past June, pembrolizumab (Keytruda) monotherapy received accelerated approval for the treatment of solid tumors with a high tumor mutational burden (TMB) on the basis of results in 10 cohorts of previously treated patients in the KEYNOTE-158 trial (NCT02628067). 1,2 Simultaneously, the FDA approved Foundation Medicine’s … seton night live