Phosphatidate phosphohydrolase
WebLipin 1 is a bifunctional intracellular protein that regulates fatty acid metabolism in the nucleus via interactions with DNA-bound transcription factors and at the endoplasmic reticulum as a phosphatidic acid phosphohydrolase enzyme (PAP-1) to catalyze the penultimate step in triglyceride synthesis. WebDec 11, 2013 · Lipid biosynthesis is essential for eukaryotic cells, but the mechanisms of the process in microalgae remain poorly understood. Phosphatidic acid phosphohydrolase or …
Phosphatidate phosphohydrolase
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WebFeb 15, 1991 · The NEM-sensitive phosphatidate phosphohydrolase activity was increased by incubating hepatocytes for 12 h with glucagon and dexamethasone, and this effect was antagonized by insulin. The NEM-sensitive phosphohydrolase is concluded to be involved in glycerolipid synthesis. The activity of the NEM-insensitive phosphohydrolase was not … WebJan 1, 2012 · Phosphatidic acid phosphohydrolase (3-sn-phosphatidate phosphohydrolase, EC 3.1.3.4), also known as PAP, catalyzes the dephosphorylation of phosphatidic acid (PtdOH) to form diacylglycerol (DAG ...
WebOct 5, 1992 · Abstract Propranolol, a beta-adrenergic receptor antagonist, also inhibits phosphatidate phosphohydrolase, the enzyme that converts phosphatidic acid into diacylglycerol. This latter effect has prompted recent use of propranolol in studies examining the importance of diacylglycerol and phosphatidic acid in cellular signalling … WebAbstract. Phosphatidic acid phosphohydrolase [PAP; E.C.3.1.3.4] catalyses the dephosphorylation of phosphatidic acid (PA) into diacylglycerol. Regulation of PAP …
Webphosphate phosphohydrolase and phosphatidate phosphohydrolase activities in the preparation are attributable to the same enzyme. I-O-Alkyd-rat-glycerol 3- phosphate was hydrolyzed with a V,, of 1.7 nmol min-’ mg-’ of protein and a K, of 270 PM. Phosphatidate phosphohydrolase (EC 3.1.3.4) catalyzes the production WebJul 7, 1989 · These two possibilities were examined by using subcellular fractions in which the Mg2+-dependent phosphatidate phosphohydrolase had been abolished by heat treatment at 55 degrees C for 15 min. Heat treatment does not affect the microsomal Mg2+-independent phosphohydrolase to any great extent.
WebMay 11, 2010 · Phosphatidic acid is converted to diacylglycerol by phosphatidate phosphohydrolase-1 before final addition of another fatty acyl-CoA to yield TAG. This final stage in the pathway is performed by diacylglycerol acyltransferase (DGAT). Two DGAT enzymes, DGAT1 and DGAT2, have been identified, which appear to have distinct …
WebPHOSPHATIDIC ACID PHOSPHOHYDROLASE Regulates Phosphatidylcholine Biosynthesis in Arabidopsis by Phosphatidic Acid-Mediated Activation of CTP:PHOSPHOCHOLINE … c101.3 rocks corpus christiWebJan 1, 2001 · The addition of phosphatidate phosphohydrolase, which had been partially purified from the particle-free supernatant, supplemented the activity of the endogenous phosphohydrolase, but it did not alter the rate of CDP-diacylglycerol formation. 3. cloudmark blocking emailWebTraductions en contexte de "50 fois plus élevée" en français-anglais avec Reverso Context : Mais 20 fois plus puissant que la vitamine C, 5 fois plus fort que le bêta-carotène et a 50 fois plus élevée que l'effet antioxydant de la vitamine E. cloudmark content scanner optonlineWebThe hydrolysis of phosphatidate by the phosphohydrolase conformed to a surface dilution kinetic model. It is concluded that the enzyme is a lipid phosphomonoesterase that could modify the balance of phosphatidate, ceramide 1-phosphate, lysophosphatidate, and sphingosine 1-phosphate relative to diacylglycerol, ceramide, monoacylglycerol, and ... cloudmarket.comWebJul 31, 1985 · In lung microsomes, labeled phosphatidic acid and diacylglycerols were synthesized from the endogenous free fatty acids and sn-[14C]glycerol 3-phosphate, which had previously been added. By addition of CDPcholine to the prelabeled microsomes the synthesis of phosphatidylcholine was measured. cloud markdown editorWebPhosphatidate phosphatase (3-sn-phosphatidate phosphohydrolase) catalyzes the conversion of phosphatidate to diacylglycerol. In the yeast, Saccharomyces cerevisiae (S. cerevisiae), phosphatidate phosphatase is associated with the membrane and cytosolic fractions of the cell. c10-14 alcohol ethoxylateWebJun 1, 1979 · Characterization of phosphatidate phosphohydrolase activity associated with chloroplast envelope membranes Author links open overlay panel Jacques Joyard , Roland Douce Show more cloudmark desktopone basic